11
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T27979 | Masilukast | ICI-D-3523,ZD-3523,ICI D-3523,MCC-847,SA-09012,D-3523 | Leukotriene Receptor |
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation. | |||
T26519 | Ablukast | Ro 23-3544 | Leukotriene Receptor |
Ablukast (Ro 23-3544) is a leuktriene receptor antagonist. Ablukast acts as an anti-asthmatic. | |||
T10501 | YM158 free base | YM-57158 | Others |
YM158 free base is a potent and selective antagonist of TXA2 and LTD4 receptor (pA2s: about 8.81 and 8.87). | |||
T10873 | CP-96486 | Others | |
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM). | |||
T27912 | LY 290324 | LY-290324,LY290324 | |
LY 290324 is an orally active, potent and selective antagonist of cysteinyl leukotriene (LTD4) receptor. | |||
T15647 | Tipelukast | MN 001,KCA 757 | Leukotriene Receptor |
Tipelukast (KCA 757) is a novel orally available leukotriene receptor antagonist with anti-inflammatory activity that reduces fibrosis and down-regulates TIMP-1, type 1 collagen.Tipelukast is used in the study of asthma. | |||
T10872 | CP-96021 hydrochloride | Others | |
CP-96021 hydrochloride is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor receptor (Kis: 34 nM and 37 nM). | |||
T27877 | LY 163443 | LY163443,LY-163443 | |
LY 163443 is an dual receptor antagonist of LTD4 and LTE4. | |||
T19674 | Verlukast | MK 0679,MK-679,L 668,019,MK 679,L 668019,L-668,019 | |
Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homog... | |||
T37652 | 5(S),6(R)-DiHETE | ||
5(S),6(R)-DiHETE is a dihydroxy polyunsaturated fatty acid and a nonenzymatic hydrolysis product of leukotriene A4 (LTA4). Mouse liver cytosolic epoxide hydrolase catalyzes the conversion of LTA4 to 5(S),6(R)-DiHETE. It ... | |||
T37980 | N-methyl Leukotriene C4 | N-methyl Leukotriene C4 | |
Produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets, leukotriene C4 (LTC4) is the parent cysteinyl leukotriene formed by the LTC4 synthase-catalyzed conjugation of glutathione t... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-03749 | CYSLTR1 Protein, Human, Recombinant (His) | Human | E. coli |
Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and... |